PATHOLOGICAL MECHANISMS OF CONNEXIN26-RELATED HEARING LOSS: POTASSIUM RECYCLING, ATP-CALCIUM SIGNALING, OR ENERGY SUPPLY?

Pathological mechanisms of connexin26-related hearing loss: Potassium recycling, ATP-calcium signaling, or energy supply?

Hereditary deafness is one of the most common human birth defects.GJB2 gene mutation is the most genetic etiology.Gap junction protein 26 (connexin26, Cx26) encoded by the GJB2 gene, which is responsible for intercellular substance transfer and signal communication, plays a critical role in hearing acquisition and maintenance.The auditory character

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A novel asynchronous access method with binary interfaces

Abstract Background Traditionally synchronous access strategies require users to comply with one or more time constraints in order to communicate intent with a binary human-machine interface (e.g., mechanical, gestural or neural switches).Asynchronous access methods are preferable, but have not been used with binary interfaces in the control of dev

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